Acetyl-L-Carnitine (ACL)
ACL, a carnitine derivative produced naturally in the body, is involved in carbohydrate and protein metabolism and in the transport of fats into the mitochondria. It increases levels of carnitine in tissues and even surpasses the metabolic potency of carnitine. ACL has become one of the most studied compounds for its antiaging effects, particularly with regard to degeneration of the brain and nervous system. Several major studies have shown that daily supplementation with ACL significantly slows the progression of Alzheimer's disease, resulting in less deterioration in memory, attention and language , and spatial abilities. It also can be used to treat other cognitive disorders, as well as depression. ACL provides numerous other benefits to many of the body's systems. It helps to limit damage caused by oxygen starvation, enhance the immune system, protect against oxidative stress, stimulate the antioxidant activity of certain enzymes, protect membranes, slow cerebral aging, prevent nerve disease associated with diabetes and sciatica, modulate hormonal changes caused by physical stress, and increase the performance-enhancing benefits of branched-chain amino acids.
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